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Home » Products » Pharmaceutical Injectables » Artesunate Injection

Artesunate Injection

Artesunate Injection
Artesunate Injection
Product Code : 09
Product Description
Category: Antimalarial
Each vial contains: Artesunate 60mg
Quality Specification: Chromatographic Purity: NLT 99.5%
Pack Size: vial


Composition :60mg
Artesunate:Artemisinin derivatives are the potent and rapidly acting blood schizonticides. These are cconcentrated in parasitized erythrocytes. Artesunate acts rapidly, stopping parasite development and preventing subsequent cytoadherence and resetting. Artesunate is well distributed and achieves high concentration in the intestines, liver and kidneys. Only a small amount of artesunate is excreted in the urine and in the stools.
Indications:Severe malaria including cerebral malaria and as a second line treatment in chloroquineresistant falciparum malaria.
Dosage : Adults : Parenteral:120gm on the first day followed by 60mg can be given on the first day itself 6 hours after the first dose.
Oral:100mg twice a day on the first day followed by 50mg twice daily for the next four days.
Children:1.2mg/kg x 5 days (maximum 60mg)
Contraindications:Not known.
Special Precaution:Avoid in pregnant woman, especially in the first trimester.
Paediatrics:May be used if chloroquine resistant.
Pregnancy:Cpmtraomdocated on 1st trimester.
Lactation:Safety not established.
Side-Effects:Transient and reversible reticulocytopenia, drug fever, drug rash, bradycardia, transient first degree heart block and transient & revesible elevation of serum transaminases.
Lactation:Safety not established.
Drug Interactions:Antimalarial action potentiated by oxidant drugs. Additive effect seen with chloroquine. Antagonistic effect seen with pyrinethamine and sulfonamides.
Purity :Not less than 99%.

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