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Home » Products » Anticancer Injectables » Doxorubicin Injection

Doxorubicin Injection

Doxorubicin Injection
Doxorubicin Injection
Product Code : 13
Product Description

Relying on our transparent business practices, we are engaged in providing quality checked Doxorubicin Injection. By incorporating advanced methodology, this injection is formulated with the help of skilled professionals using high grade chemicals. Demanded in hospitals, clinics and health care centers, the provided injection is highly effective for curing bladder, blood, bone, stomach, testicle and ovary cancer. In addition, we provide this Doxorubicin Injection in hygienic packaging at the most economical prices.

Key points:

  • Balanced chemical composition
  • No side effects
  • Free from adulteration
  • Quick results

 

Category: Anti neo-plastic 
Each vial contains:- Doxorubicin¦.. 10mg and 50mg
Quality Specification: Chromatographic Purity: NLT 99%

It is a antitumour antibiotic and finds a useful application in acute leukemia & in many solid tumours. Doxorubicin is capable of cusing breaks in DNA strands and have mutagenic and carcinogenic potential. Maximum action is exerted at S phase, but toxicity is usually exhibited in G2 phase.


Composition :

Each vial contains: 
Doxorubicin Hydrochloride.10mg, 50mg, 100mg 
Lactose Monohydrate 50mg, 200mg, 500mg

Indications :

Doxorubicin has been used successfully to produce regression in disseminated neoplastic conditions such as acute lymphoblastic leukemia, acute myeloblasticleukemia, Wilms' tumor, neuroblastoma, soft tissue and bone sarcomas, breast carcinoma, ovarian carcinoma, transitional cell bladder carcinoma, thyroid carcinoma, gastric carcinoma, Hodgkin's disease, malignant lymphoma and bronchogenic carcinoma in which the small cell histologic type is the most responsive compared to other cell types.

Contraindications :

In patients with history of hypersensitivity to the drug, pregnancy, location.

Pharmacological action:

: It is a antitumour antibiotic and finds a useful application in acute leukemia & in many solid tumours. Doxorubicin is capable of cusing breaks in DNA strands and have mutagenic and carcinogenic potential. Maximum action is exerted at S phase, but toxicity is usually exhibited in G2 phase

Adverse Effects :

: Cardiotoxicity, alopecia, Bone marrow depression, alopecia, cardiomyopathy, stomatitis, vomiting and local tissue damage.

Dosage :

1.2-2.4 mg/kg body wt or 60-75 mg/sq metre of body surface given as a single dose every 3 week by slow i.v. inj. Doxorubicin has been used concurrently with other approved chemotherapeutic agents. Evidence is available that in some types of neoplastic disease combination chemotherapy is superior to single agents. The benefits and risks of such therapy continue to be elucidated. When used in combination with other chemotherapy drugs, the most commonly used dosage of doxorubicin is 40 to 60 mg/m2 given as a single intravenous injection every 21 to 28 days.

Drug interaction:

Doxorubicin is extensively metabolized by the liver. Changes in hepatic function induced by concomitant therapies may affect doxorubicin metabolism, pharmacokinetics, therapeutic efficacy, and/or toxicity. Toxicities associated with doxorubicin, especially hematologic and gastrointestinal events, may be increased when doxorubicin is used in combination with other cytotoxic drugs.

Precautions:

ECG changes, arrhythmias, hypotension, or be delayed congestive heart failure.Doxorubicin may cause heart problems, including possibly fatal heart failure. Heart problems may occur durin doxorubicin therapy or months to years after receiving this medication



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